BIOCORE JOURNALS

What not to do During Noninvase Mechanical Ventilation in Acute Setting

Antonela Vicente*, Salvador Díaz-Lobato

Pneumological Department. Ramón y Cajal Hospital, Alcalá de Henares University

Unpaired Anterior Cerebral Artery Associated with Double Origin of Vertebral Artery: Case Report and Genetic Consideration

Maryna A. Kornieieva*, Azmy M. Hadidy, Eman S. Zayed, Suzan H. Hinno

The case demonstrates the co-development of two rare anatomical variations of the vascular pattern in 76-year-old man patient. By means of magnetic cerebral angiography the unusual shape of circle of Willis with fusion of the second segment of the anterior cerebral artery and absence of the anterior communicating artery was uncovered. Additionally, the duplicated cervical vertebral artery with one limb attached to the aortic arch distal to the origin of the left subclavian artery, and the other – from the left subclavian artery at the level of origin of the thyrocervical trunk was revealed during interpretation of angiographic images of the head and neck. While double origin of the vertebral artery does not influence the cerebral circulation directly, the unpaired anterior cerebral artery plays a predisposal role in the development of cerebral ischemic disorders and aneurysms.

The co-formation of these rare vascular patterns implies misbehavior of the primary epithelial cells due to dis-coordination of the genetic regulatory factors during the early vascular development. The aims of this paper are: 1) to trace the phylogenetic and embryologic formation of the anterior cerebral and vertebral arteries; 2) to summarize the known genetic pathways of regulation of angiogenesis; 3) to emphasize the importance of vascular plasticity of the cerebral circulation.

A Study of Mental Health & Life Satisfaction Among Aged People

Muzafar Hussain Kawa*, Sayema Shaban, Mohd Ilyas Khan, Mohd Owais Khan

The present research endeavor was aimed to assess Mental Health and Life Satisfaction among aged people. The sample of the study consisted of 200 aged people, of which 120 were males and 80 were females. Mental Health Inventory (MHI-38) and the Satisfaction with Life Scale (SWLS) were used. Pearson’s correlation and t-test were used for the analysis of data. The results indicated that there is a positive correlation between mental health and life satisfaction among aged people. The results also revealed that there is a significant difference in mental health & life satisfaction among aged people as far as their family type is concerned. The results revealed that there is not a significant difference in mental health & life satisfaction among aged people with respect to their gender. 

Serum Uric Acid Level in Patients with Diabetes Mellitus Attending a Tertiary Care Hospital

Kashif Ali Fazlani*, Bedarbakhat Khan, Rehan Ahmed Jokhio

Introduction: Serum uric acid (SUA) is positively associated with serum glucose levels in healthy subjects. Recent studies have demonstrated that UA levels are higher in subjects with prediabetes and early Type-II diabetes then in healthy controls. Furthermore, an elevated serum UA level was found to increase chances for developing Type-II diabetes in individuals with impaired glucose tolerance.

Objectives: To determine the mean serum uric acid level in patients with diabetes mellitus attending a tertiary care hospital.

Study Design: Cross-sectional Study.

Setting: All medical wards of Liaqat University of medical and health sciences. Hyderabad, Jamshoroo

Duration: Six months from June 23, 2010 to December 22, 2010 Subjects and methods: A total of 138 cases fulfilling the inclusion criteria diagnosed as defined earlier were enrolled in the study by the Principle Investigator (PI). Brief history was taken regarding the duration of DM. A serum uric acid request was made from the institutional laboratory. Serum uric acid level was noted. This information as well as data regarding age, gender, duration of diabetes Mellitus, and Hypertension status was entered in the proforma.

Results: The mean age was 57.5 ± 12.3 years with Male: Female = 1.2: 1. Overall mean serum uric acid was 13.3 ±2.5 mg/dL (Min – Max = 3 – 16 mg/dL). Out of 138 cases, 84 (60.9%) of cases had serum uric acid level > 7 mg/dL. The mean value of serum uric acid was 15.1 ±1.9 mg/dL in men and 11.2 ±3.1 mg/dL in women.

Conclusion: In conclusion, this study showed significantly elevated serum uric acid 13.3 ±2.5 mg/dL in patients with Type-II diabetes.